Melting

Melting - Nearest-neighbor compilation of nucleic acid hybridation

Melting computes, for a nucleic acid duplex, the enthalpy and entropy of the helix-coil transition, and then its melting temperatures. Three types of hybridisation are possible: DNA/DNA, DNA/RNA, and RNA/RNA. The program uses the method of nearest-neighbors. The set of thermodymanic parameters can easily be changed, for instance following an experimental breakthrough. The program is coded in ISO C and can be compiled on any operating system. Some Perl scripts are provided to show how melting can be used as a block to construct more ambitious programs.

Obtaining

Web page	http://www.pasteur.fr/recherche/unites/neubiomol/meltinghome.html
Source tarball	http://www.pasteur.fr/recherche/unites/neubiomol/SOFTWARES/melting4_2e.tar.gz

Version 4.2 (stable) released on 2002-02-21

Licensed under The GNU General Public License, Version 2 or later.

This is a GNU package.

Documentation

User manual included and available in HTML format from http://www.pasteur.fr/recherche/unites/neubiomol/SOFTWARES/melting/melting.html

Support contacts

Help List	<melting@listes.pasteur.fr> http://sympa.pasteur.fr/wws/info/melting
Developer List	<melting@listes.pasteur.fr> http://sympa.pasteur.fr/wws/info/melting
Bug List	<melting@listes.pasteur.fr> http://sympa.pasteur.fr/wws/info/melting

Project contacts

Maintainers	Nicolas Le Novere <lenov@pasteur.fr>
Developers	Nicolas Le Novere <lenov@pasteur.fr>
Contributors	Nicolas Joly <njoly@pasteur.fr> Catherine Letondal <letondal@pasteur.fr> Nirav Merchant <nirav@biosci.arizona.edu>

Related information

Interfaces	command line, X Window System, web
Source languages	C, Perl
Use requirements	Perl, Perl/tk
Weak prerequisites	Perl, Perl/tk

Entry information

License verified by	Janet Casey <jcasey@gnu.org> on 2001-01-31
Entry compiled by	Janet Casey <jcasey@gnu.org>

Categories

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